Bleeding for You

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What is Hemophilia?
Do I have hemophilia?
How can I get hemophilia?
Where is the gene that causes hemophilia?
How do the doctors see if I have hemophilia?
How do I get rid of hemophilia?
Where can I learn more about hemophilia?
Where did I get all of this information?
How can I get hemophilia?

On this page you can learn how this disease is inherited from your parents. At this point there is nothing you can do to save yourself but you can at least know if your children will get it.

Hemophilia A:

When a normal person gets an injury and starts to bleed, a process begins within his body. As the body responds to the injury, a factor within the body is activated to clot the blood. This factor is factor, and when activated it sets off a whole chain of factors, which all activate each other one by one. When the final one is activated, the clot begins to form. Along this chain is a factor called factor 8, which is the factor that affects Hemophilia A. In Hemophilia A, the factor 8 is altered or absent. If the factor 8 is altered then this slows down the process, so clotting occurs much slower. The alteration in the factor occurs because one part of the makeup of the factor is changed, like an adenine is changed to a thymine. However, in a much more severe case, if the factor is absent, then the process cannot occur at all. Therefore, clotting cannot occur without treatment. This occurs when a whole part of the persons DNA is changed, such as a part being switched around.

Mutation:

A mutation can occur during meiosis when the child is being produced. This occurs when one of the genes from the mother is altered and becomes the recessive gene. The recessive gene is then transmitted to the male child. As in other genectic diseases, mutation is how the disease first started.

Hemophilia B:

The same process for Hemophilia A occurs as within Hemophilia B. There is change, which occurs to affect one of the factors on the chain. However, in Hemophilia B, the factor affected is factor 9, not factor 8 as in Hemophilia A. As in Hemophilia A, the presence of the factor affects how severe a case occurs in the person.

Seen in this picture is the inheritance of the disease throughout the European royal family, where it was prominent

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Now, let's see where the gene for hemophilia is located:

Where is the gene that causes hemophilia?